Russian Clinical Laboratory DiagnosticsRussian Clinical Laboratory DiagnosticsКлиническая лабораторная диагностика0869-20842412-1320Eco-Vector64604310.17816/cld646043EOPADKReviewsОбзорыReview ArticleScreening for iron deficiency conditions as an effective tool for donor blood managementСкрининг железодефицитных состояний как эффективный инструмент менеджмента крови доноровhttps://orcid.org/0000-0003-2583-9956ChirkovaKarina S.ЧирковаКарина Сергеевна
Russian Federation
Korish112@mail.ruhttps://orcid.org/0000-0001-7542-851X7119-8871KostinAlexander I.КостинАлександр Игоревич
Russian Federation

MD, Cand. Sci. (Medicine)

канд. мед. наук

KostinAI@sklif.mos.ruhttps://orcid.org/0000-0002-6405-34222249-6272LugovskayaSvetlana A.ЛуговскаяСветлана Алексеевна
Russian Federation

MD, Dr. Sci. (Medicine), Professor

д-р мед. наук, профессор

slugovskaya@mail.ruhttps://orcid.org/0009-0007-8925-8727SochilovaNatalia A.СочиловаНаталья Александровна
Russian Federation
sochilova.nataliya@yandex.ruN.V. Sklifosovsky Research Institute for Emergency MedicineНаучно-исследовательский институт скорой помощи им. Н.В. СклифосовскогоRussian Medical Academy of Continuous Professional EducationРоссийская медицинская академия непрерывного профессионального образованияThe industry center for the development and implementation of information systemsОтраслевой центр разработки и внедрения информационных систем150720252507202569113653751301202528032025Copyright ©; 2024, Chirkova K.S., Kostin A.I., Lugovskaya S.A., Sochilova N.A.Copyright ©; 2024, Чиркова К.С., Костин А.И., Луговская С.А., Сочилова Н.А.2024Chirkova K.S., Kostin A.I., Lugovskaya S.A., Sochilova N.A.Чиркова К.С., Костин А.И., Луговская С.А., Сочилова Н.А.https://creativecommons.org/licenses/by-nc-nd/4.0https://kld-journal.fedlab.ru/0869-2084/article/view/646043

Regular blood donation may lead to the depletion of iron stores in donors, which affects their health and impacts the quality of collected blood components. This review highlights the relevance of monitoring iron metabolism in donor practice and its role in blood donor management systems.

A scientific data search was conducted from February to October 2024 using the following electronic databases: PubMed, Scopus, Web of Science, eLIBRARY.RU, and Google Scholar. The analysis included original research articles, systematic reviews, meta-analyses, and clinical guidelines.

Modern approaches to donor potential management should include screening of iron metabolism indicators, personalized donation interval planning, and timely prevention of iron deficiency conditions. The implementation of iron status monitoring programs ensures donor safety, optimizes donation frequency, and helps maintain stable supplies of blood components of appropriate quality.

The authors place particular emphasis on the cost-effectiveness of preventive measures compared to the treatment of developed iron deficiency, which is crucial for the rational use of blood service resources.

Регулярное донорство крови может приводить к истощению запасов железа в организме доноров, что влияет на их здоровье и отражается на качестве заготавливаемых компонентов крови. В настоящем обзоре авторы рассматривают актуальность мониторинга обмена железа в донорской практике и его роль в системе менеджмента донорской крови.

Поиск научной литературы проводили в период с февраля по октябрь 2024 г. с использованием следующих электронных баз данных: PubMed, Scopus, Web of Science, eLIBRARY.ru и Google Scholar. В анализ были включены оригинальные исследования, систематические обзоры, метаанализы и клинические рекомендации.

Современные подходы к управлению донорским потенциалом должны включать скрининг показателей обмена железа, персонализированный подход к интервалам между донациями и своевременную профилактику железодефицитных состояний. Внедрение программ мониторинга статуса железа позволяет обеспечить безопасность доноров, оптимизировать донорский режим и поддерживать стабильные запасы компонентов крови надлежащего качества.

Особое внимание авторы уделяют экономической эффективности превентивных мер по сравнению с коррекцией уже развившегося дефицита железа, что имеет важное значение для рационального использования ресурсов службы крови.

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