Современные представления о фибробластах эндоневрия

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Целью настоящего обзора явилось обобщение современных представлений о фибробластах эндоневрия периферических нервных проводников и их роли в репаративной регенерации нерва. Наряду со шванновскими клетками и макрофагами фибробласты являются основными по функциональной значимости клетками эндоневрия. В литературе имеется мало сведений об особенностях фибробластов и их роли в регенерации поврежденных нервных проводников. В обзоре представлены данные последних лет о морфофункциональных особенностях фибробластов эндоневрия, их происхождении в онтогенезе и их функциях. Дана характеристика иммуногистохимических маркеров, используемых для их идентификации. Подчеркивается необходимость исследования взаимодействий фибробластов с другими клетками нерва для выяснения их роли в регенерации нервных проводников после повреждения.

Об авторах

Е. С. Петрова

Институт экспериментальной медицины

Email: iempes@yandex.ru
Санкт-Петербург, Россия

Е. А. Колос

Институт экспериментальной медицины

Санкт-Петербург, Россия

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