The Astonishing Accomplishment of Biological Drug Delivery using Lipid Nanoparticles: An Ubiquitous Review
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1. | Title | Title of document | The Astonishing Accomplishment of Biological Drug Delivery using Lipid Nanoparticles: An Ubiquitous Review |
2. | Creator | Author's name, affiliation, country | Devesh Kapoor; Department of Pharmaceutical Technology, Dr. Dayaram Patel Pharmacy College |
2. | Creator | Author's name, affiliation, country | Shirisha Chilkapalli; Department of Pharmaceutical Technology, Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University |
2. | Creator | Author's name, affiliation, country | Bhupendra Prajapati; Department of Pharmaceutical Technology, Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University |
2. | Creator | Author's name, affiliation, country | Paul Rodriques; Department of Pharmaceutical Technology, Krishna School of Emerging Technology and Applied Research |
2. | Creator | Author's name, affiliation, country | Ravish Patel; Department of Pharmaceutical Technology, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology |
2. | Creator | Author's name, affiliation, country | Sudarshan Singh; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University |
2. | Creator | Author's name, affiliation, country | Sankha Bhattacharya; Department of Pharmaceutics, School of Pharmacy & Technology Management, SVKMS NMIMS School of Pharmacy and Technology Management |
3. | Subject | Discipline(s) | |
3. | Subject | Keyword(s) | Lipid nanoparticles; biologicals; nucleic acids; protein-based products; vaccines; DNA/RNA therapies. |
4. | Description | Abstract | :Biotech drugs, including proteins, hormones, enzymes, DNA/RNA therapies, and cell-based treatments, are gaining popularity due to their effectiveness. However, effective delivery systems are needed to overcome administration challenges. Lipid nanoparticles (LNPs) have emerged as promising carriers for various therapies. LNPs are biocompatible, less likely to cause adverse reactions, and can stabilize delicate biological drugs, enhancing their stability and solubility. Scalable and cost-effective manufacturing processes make LNPs suitable for largescale production. Despite recent research efforts, challenges in stability, toxicity, and regulatory concerns have limited the commercial availability of LNP-based products. This review explores the applications, administration routes, challenges, and future directions of LNPs in delivering biopharmaceuticals. |
5. | Publisher | Organizing agency, location | Bentham Science |
6. | Contributor | Sponsor(s) | |
7. | Date | (DD-MM-YYYY) | 01.01.2024 |
8. | Type | Status & genre | Peer-reviewed Article |
8. | Type | Type | Research Article |
9. | Format | File format | |
10. | Identifier | Uniform Resource Identifier | https://kld-journal.fedlab.ru/1389-2010/article/view/644606 |
10. | Identifier | Digital Object Identifier (DOI) | 10.2174/0113892010268824231122041237 |
11. | Source | Title; vol., no. (year) | Current Pharmaceutical Biotechnology; Vol 25, No 15 (2024) |
12. | Language | English=en | |
13. | Relation | Supp. Files | |
14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
15. | Rights | Copyright and permissions |
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