Resorption Dynamics of Hydroxyapatite-, Wollastonite-, and Gelatin-Based Granules in Tris-Buffer

A. P. Solonenko; Солоненко А. П.; A. E. Shevchenko; Шевченко А. Е.; D. A. Polonyankin; Полонянкин Д. А.

doi:10.31857/S0002337X23030144

Resorption Dynamics of Hydroxyapatite-, Wollastonite-, and Gelatin-Based Granules in Tris-Buffer

Authors: Solonenko A.P.¹, Shevchenko A.E.¹, Polonyankin D.A.²
Affiliations:
1. Omsk State Medical University, 644099, Omsk, Russia
2. Omsk State Technical University, 644050, Omsk, Russia
Issue: Vol 59, No 3 (2023)
Pages: 341-348
Section: Articles
URL: https://kld-journal.fedlab.ru/0002-337X/article/view/668326
DOI: https://doi.org/10.31857/S0002337X23030144
EDN: https://elibrary.ru/YUHYSG
ID: 668326

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Abstract
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Abstract

Results of an in vitro study demonstrate that, when brought in contact with tris-buffer, granules based on gelatin and synthetic ceramic powders containing varied percentages of Са10(РО4)6(ОН)2 and β-СаSiO3 rapidly degrade and swell, increasing in size by up to a factor of 1.2. After that, they gradually degrade, releasing calcium ions and phosphate and silicate anions to the solution. The systems with materials containing 20 to 60 wt % calcium silicate have been found to differ little in the concentrations of these ions. The weight loss of the composites, due to dissolution of the mineral components and gelatin, has been shown to exceed that of the apatite and wollastonite granules.

Keywords

biomaterials, dissolution, granulated materials, calcium phosphates, calcium silicates

References

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