Piezopulsometric analysis of the functional state of human cardiovascular system

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Abstract

This paper expounds how to apply in practice the developed computer method of arterial piezopulsometry, with examples, for non-invasive express analysis of the functional state and the nature of autonomic regulation of the cardiovascular system in patients of different ages and health conditions. The participation and role of the contractile component of myocytes of the left ventricle of the heart is assessed as a universal muscle effector, providing both the basic pumping function of the heart and the implementation of the autonomic regulation of heart contraction using peripheral neurohumoral mechanisms that maintain the optimal level of cardiac hemodynamics. This analysis enhances the predictive value of early non-invasive pulsometric diagnostics of the individual functional state and nature of regulation of human cardiovascular system during ontogenesis. This knowledge helps identify the risk of reducing the ability of the cardiovascular system, which has developed during its evolution, to maintain dynamic balance, self-regulation and adaptation to changing environmental conditions, which is associated with a violation of the body’s homeostasis.

About the authors

V. P Nesterov

I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences

Email: nesterov@iephb.ru
St. Petersburg, Russia

A. I Burdygin

I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences

St. Petersburg, Russia

K. B Ivanov

I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences

St. Petersburg, Russia

K. V Sobol

I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences

St. Petersburg, Russia

I. V Shemarova

I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences

St. Petersburg, Russia

References

  1. Методы исследования сердечно-сосудистой системы, Руководство по кардиологии (под ред. Е.И. Чазова), 2 (М. 1982), Т. 2.
  2. N. Ferrara, K. Komici, G. Corbi, et al., Front Physiol., 4, 396 (2014).
  3. I. V. Shemarova, V. P. Nesterov, L. V. Emelyanova, et al., Front. Bioscience-Scholar, 13 (2), 105 (2021).
  4. G. F. Mitchell, H. Parise, E. J. Benjamin, et al., Hypertension, 43, 1239 (2004).
  5. A. Schumann and K. Bar, PhysioNet, doi: 10.13026/2hsy-t491 (2021).
  6. Н. Р. Палеев и И. М. Каевицер, Атлас гемодинамических исследований в клинике внутренних болезней (Медицина, М., 1975).
  7. S. V. Nesterov, Human Physiol., 31 (1), 70 (2005).
  8. В. П. Нестеров, А. И. Бурдыгин и С. В. Нестеров, Физиология человека, 43 (6), 54 (2017).
  9. В. П. Нестеров, А. И. Бурдыгин, К. Б. Иванов и др., Журн. эволюц. биохимии и физиологии, 31 (6), 433 (2019).
  10. Heart rate variability. Standarts of measurement, physiological interpretation, and clinical use, Eur. Heart J. 17 (3), 354 (1995).
  11. J. A. Taylor and D. L. Eckberg, Circulation, 93 (8), 1527 (1996).
  12. W. N. Wilmer, J. D. Scott, I. B. Wilkinson, et al., J. Clin. Hyperten., 10 (4), 295 (2008).
  13. В. П. Нестеров, М. Ф. Баллюзек, А. О. Конради и др., Успехи геронтологии, 29 (1), 107 (2016).
  14. С. А. Котельников, А. Д. Ноздрачев, М. М. Одинак и др., Физиология человека, 28 (1), 130 (2002).
  15. J. H. Skotte and J. Kristiansen, Biomed. Eng. Online, 13, 138 (2014).
  16. В. P. Nesterov, A. I. Burdygin, K. B. Ivanov, et al., Adv. Gerontology, 12 (2), 147 (2022).
  17. V. P. Nesterov, A. I. Burdygin, K. B. Ivanov, et al., Biophysics, 68 (1), 21 (2023).

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