电邮这篇文章 The Role of Changes in Structure and Dynamics of Chromatin Due to COVID-19
- 作者: Bigildeev A.E.1, Alekseev V.I.2, Gribkova A.K.2, Timokhin G.S.3, Komarova G.A.4, Shaytan A.K.2,3
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隶属关系:
- National Medical Research Center for Hematology
- Department of Biology, Lomonosov Moscow State University
- Laboratory of Bioinformatics, Faculty of Computer Science, National Research University Higher School of Economics
- Department of Physics, Lomonosov Moscow State University
- 期: 卷 60, 编号 1 (2024)
- 页面: 16-41
- 栏目: ОБЗОРНЫЕ И ТЕОРЕТИЧЕСКИЕ СТАТЬИ
- URL: https://kld-journal.fedlab.ru/0016-6758/article/view/667007
- DOI: https://doi.org/10.31857/S0016675824010027
- ID: 667007
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详细
The COVID-19 pandemic has become a serious challenge for the healthcare system and the economy of many states, and understanding the molecular mechanisms of the pathogenesis of this disease has become a significant challenge for modern science. At the same time, for the first time, a number of high-precision and high-throughput methods for analyzing molecular processes were available to scientists, including technologies for studying changes in chromatin at the genomic level. In this review, we discuss various modern methods that have been used or can be used to study changes in the structure and dynamics of chromatin during infection with SARS-CoV-2, present the results of currently available studies on the role of these changes in the pathogenesis of COVID-19, and in conclusion we review the currently known molecular mechanisms of chromatin modulation that occur during infection with SARS-CoV-2.
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作者简介
A. Bigildeev
National Medical Research Center for Hematology
编辑信件的主要联系方式.
Email: shaytan_ak@mail.bio.msu.ru
俄罗斯联邦, Moscow
V. Alekseev
Department of Biology, Lomonosov Moscow State University
Email: shaytan_ak@mail.bio.msu.ru
俄罗斯联邦, Moscow
A. Gribkova
Department of Biology, Lomonosov Moscow State University
Email: shaytan_ak@mail.bio.msu.ru
俄罗斯联邦, Moscow
G. Timokhin
Laboratory of Bioinformatics, Faculty of Computer Science, National Research University Higher School of Economics
Email: shaytan_ak@mail.bio.msu.ru
俄罗斯联邦, Moscow
G. Komarova
Department of Physics, Lomonosov Moscow State University
Email: shaytan_ak@mail.bio.msu.ru
俄罗斯联邦, Moscow
A. Shaytan
Department of Biology, Lomonosov Moscow State University; Laboratory of Bioinformatics, Faculty of Computer Science, National Research University Higher School of Economics
Email: shaytan_ak@mail.bio.msu.ru
俄罗斯联邦, Moscow; Moscow
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