The Influence of Antidiabetic Medications on Diagnostic Accuracy of Plasma Tau 217 Assay


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Hisham Altayb

Department of Biochemistry, Faculty of Science, King Abdulaziz University

Email: info@benthamscience.net

Fahad Al-Abbasi

Department of Biochemistry, Faculty of Science, King Abdulaziz University

Email: info@benthamscience.net

Firoz Anwar

Department of Biochemistry, Faculty of Science, King Abdulaziz University

Author for correspondence.
Email: info@benthamscience.net

References

  1. Ashton NJ, Brum WS, Di Molfetta G, et al. Diagnostic accuracy of a plasma phosphorylated Tau 217 immunoassay for Alzheimer disease pathology. JAMA Neurol 2024; 81(3): 255-63. doi: 10.1001/jamaneurol.2023.5319 PMID: 38252443
  2. Zhang S, Zhong J, Xu L, et al. Truncated Dyrk1A aggravates neuronal apoptosis by inhibiting ASF‐mediated Bcl‐x exon 2b inclusion. CNS Neurosci Ther 2024; 30(4): e14493. PMID: 37864462
  3. Lee H, Hoe HS. Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling. Pharmacol Res 2023; 190: 106725. doi: 10.1016/j.phrs.2023.106725 PMID: 36907286
  4. Delabar JM, Gomes MAGB, Fructuoso M, et al. EGCG-like non-competitive inhibitor of DYRK1A rescues cognitive defect in a down syndrome model. Eur J Med Chem 2024; 265: 116098. doi: 10.1016/j.ejmech.2023.116098 PMID: 38171148
  5. Moran C, Lacy ME, Whitmer RA, et al. Glycemic control over multiple decades and dementia risk in people with type 2 diabetes. JAMA Neurol 2023; 80(6): 597-604. doi: 10.1001/jamaneurol.2023.0697 PMID: 37067815
  6. Sadybekov AV, Katritch V. Computational approaches streamlining drug discovery. Nature 2023; 616(7958): 673-85. doi: 10.1038/s41586-023-05905-z PMID: 37100941

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