An Acetone-Neutral Adsorption-Based Sensor of Exhaled-Air Humidity for Diagnosis of Diabetes Mellitus

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Abstract

An acetone-neutral adsorption-based sensor of exhaled air humidity was developed for potential use in the diagnosis of diabetes mellitus. The sensor was made use a molecular sieve of KA zeolite, a granule of which was is glued to the plate of the quartz resonator of longitudinal oscillations. The sensor sensitivity threshold for water vapor was 0.05% of relative humidity. Due to the molecular-sieve effect, the acetone molecules penetrate to the zeolite pores only at concentrations above ~5%. Therefore, the sensor is sensitive to water-vapor adsorption, but not to acetone vapor and other volatile organic compounds that are present in exhaled air. The content of acetone and other biomarkers of diseases can be detected by a special sensor intended for the diagnosis of diabetes mellitus, lung cancer, alimentary-system organ dysfunction, and other diseases.

About the authors

V. N. Simonov

Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences; National Research Nuclear University “Moscow Engineering Physics Institute”

Email: simonov.valer@yandex.ru
119071, Moscow, Russia; 115409, Moscow, Russia

A. A. Fomkin

Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences

Email: simonov.valer@yandex.ru
119071, Moscow, Russia

A. V. Shkolin

Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences

Email: simonov.valer@yandex.ru
119071, Moscow, Russia

I. E. Menshikov

Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences

Author for correspondence.
Email: simonov.valer@yandex.ru
119071, Moscow, Russia

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Copyright (c) 2023 В.Н. Симонов, А.А. Фомкин, А.В. Школин, И.Е. Меньщиков