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Authors
Epidermal Growth Factor Receptor as a Target for Anti-Cancer Agent Design
Cao J., Fang H., Wang B., Ma C., Xu W.
Modulation of MMPs by Cell Surface Integrin Receptor α5β1
Pal S., Kumar Ganguly K., Moulik S., Chatterjee A.
Combination Therapy with Arsenic Trioxide for Hematological Malignancies
Takahashi S.
Evolving Therapies and FAK Inhibitors for the Treatment of Cancer
Bullard Dunn K., Heffler M., M. Golubovskaya V.
Design, Synthesis and Biological Evaluation of Quinoxalin-2(1H)-one Derivatives as EGFR Tyrosine Kinase Inhibitors
Qin X., Han X., Hu L., Li Z., Geng Z., Wang Z., Zeng C., Xiao X.
Mouse Induced Glioma-Initiating Cell Models and Therapeutic Targets
Kondo T.
Mitoxantrone Targets the ATP-binding Site of FAK, Binds the FAK Kinase Domain and Decreases FAK, Pyk-2, c-Src, and IGF-1R In Vitro Kinase Activities
M. Golubovskaya V., Ho B., Zheng M., Magis A., Ostrov D., G. Cance W.
Therapeutic Exploitation of Apoptosis and Autophagy for Glioblastoma
Kogel D., Fulda S., Mittelbronn M.
Discovery of Small Molecule c-Met Inhibitors: Evolution and Profiles of Clinical Candidates
Underiner T., Herbertz T., Miknyoczki S.
Mitogen-activated Protein Kinase Kinase 6-fusion Protein (MAP2K6-FP) Potentiates the Anti-tumor effects of Paclitaxel in Ovarian Cancer
Yuan J., Kang J., Liao H., Wang X., Nie M., Shuai R., Deng C.
Anaplastic Lymphoma Kinase as a Therapeutic Target in Anaplastic Large Cell Lymphoma, Non-Small Cell Lung Cancer and Neuroblastoma
Cheng M., R. Ott G.
Focal Adhesion Kinase Controls Prostate Cancer Progression Via Intrinsic Kinase and Scaffolding Functions
Figel S., H. Gelman I.
Regulatory Cascades of Protein Phosphatases: Implications for Cancer Treatment
Jailkhani N., K. Chaudhri V., V.S. Rao K.
First Approval of Pacritinib as a Selective Janus Associated Kinase-2 Inhibitor for the Treatment of Patients with Myelofibrosis
De S.
Erlotinib in Glioblastoma - Lost in Translation?
Karpel-Massler G., Andrew Westhoff M., E. Kast R., Rainer Wirtz C., Halatsch M.
New Targeted Therapies for Anaplastic Thyroid Cancer
Antonelli A., Fallahi P., Ulisse S., Martina Ferrari S., Minuto M., Saraceno G., Santini F., Mazzi V., D'Armiento M., Miccoli P.
Therapeutic Strategies to Target Multiple Kinases in Glioblastoma
Sathornsumetee S.
BRAF as a Target for Cancer Therapy
Dienstmann R., Tabernero J.
The Microarray Gene Profiling Analysis of Glioblastoma Cancer Cells Reveals Genes Affected by FAK Inhibitor Y15 and Combination of Y15 and Temozolomide
Huang G., Ho B., Conroy J., Liu S., Qiang H., Golubovskaya V.
Upregulation of Focal Adhesion Kinase by 14-3-3ε via NFκB Activation in Hepatocellular Carcinoma
Ko B., Jan Y., Chang T., Liang S., Chen S., Liu T., Wu Y., Wang J., Liou J.
Targeting Cancer Using Fragment Based Drug Discovery
P. Turnbull A., M. Boyd S.
Nitroimidazoles as Anti-Tumor Agents
Liu K., Zhu H.
The Ubiquitin+Proteasome Protein Degradation Pathway as a Therapeutic Strategy in the Treatment of Solid Tumor Malignancies
J. Driscoll J., Minter A., A. Driscoll D., K. Burris J.
An Orally Bioavailable c-Met Kinase Inhibitor Potently Inhibits Brain Tumor Malignancy and Growth
Guessous F., Zhang Y., diPierro C., Marcinkiewicz L., Sarkaria J., Schiff D., Buchanan S., Abounader R.
MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells
Golubovskaya V., Sumbler B., Ho B., Yemma M., Cance W.
Recent Developments on Thiourea Based Anticancer Chemotherapeutics
Kumar V., Chimni S.
Focal Adhesion Kinase Regulates Expression of Thioredoxin-interacting Protein (TXNIP) in Cancer Cells
Ho B., Huang G., Golubovskaya V.
Hypoxia-Inducible Factors and Sphingosine 1-Phosphate Signaling
Cuvillier O., Ader I.
Development of Focal Adhesion Kinase Inhibitors in Cancer Therapy
Wee Ma W.
TEM8 Targeted Cancer Therapy
E. Frankel A., Carter C., Kuo S., Woo J., Mauldin J., Liu J.
The Microarray Gene Profiling Analysis of Glioblastoma Cancer Cells Reveals Genes Affected by FAK Inhibitor Y15 and Combination of Y15 and Temozolomide
Huang G., Ho B., Conroy J., Liu S., Qiang H., Golubovskaya V.
Deregulation of PI3K/Akt/mTOR Signaling Pathways by Isoflavones and its Implication in Cancer Treatment
Ahmad A., Biersack B., Li Y., Kong D., Bao B., Schobert R., Padhye S., Sarkar F.
A Small-molecule Inhibitor, 5'-O-Tritylthymidine, Targets FAK and Mdm-2 Interaction, and Blocks Breast and Colon Tumorigenesis in vivo
M. Golubovskaya V., L. Palma N., Zheng M., Ho B., Magis A., Ostrov D., G. Cance W.
S1P Regulation of Macrophage Functions in the Context of Cancer
Weigert A., Weichand B., Brune B.
FAK and p53 Protein Interactions
M. Golubovskaya V., G. Cance W.
Dual-Specificity MAP Kinase Phosphatases as Targets of Cancer Treatment
Nunes-Xavier C., Roma-Mateo C., Rios P., Tarrega C., Cejudo-Marin R., Tabernero L., Pulido R.
Uses of Cyclohexan-1,3-diones to Synthesis Xanthenes Derivatives with Anti-proliferative Activity Against Cancer Cell Lines and their Inhibitions Toward Tyrosine Kinases
Mohareb R., Abdo N., Ibrahim M.
Focal Adhesion Kinase Regulates Expression of Thioredoxin-interacting Protein (TXNIP) in Cancer Cells
Ho B., Huang G., Golubovskaya V.
EGFRIndb: Epidermal Growth Factor Receptor Inhibitor Database
Yadav I., Singh H., Khan M., Chaudhury A., Raghava G., Agarwal S.
Targeting the Fibroblast Growth Factor Receptors for the Treatment of Cancer
Lemieux S., Hadden M.
CDK1 Hyperphosphorylation Maintenance Drives the Time-course of G2-M Cell Cycle Arrest after Short Treatment with NAMI-A in Kb Cells
Bergamo A., Delfino R., Casarsa C., Sava G.
Regulation of Sphingosine Kinase in Hematological Malignancies and Other Cancers
M. Pitson S., A. Powell J., S. Bonder C.
PRL-3, An Emerging Marker of Carcinogenesis, Is Strongly Associated with Poor Prognosis
Guzinska-Ustymowicz K., Pryczynicz A.
Recent Advances and Future Directions in the Management of Metastatic Renal Cell Carcinoma
Ansari J., Glaholm J., McMenemin R., James N., Hussain S.
Computational Modelling Strategies for Exploring Triazolopyridazine PIM1 Kinase Inhibitors as Anticancer Agents
Walhekar V., Bagul C., Kumar D., Achaiah G., Muthal A., Kulkarni R., Basavarju M.
Synthesis and Biological Evaluation of Thiazole-based Fibroblast Growth Factor Receptor-1 Inhibitors
Khanfar M., Salman I., Ameer O.
Advances in the Researches on the Biological Activities and Inhibitors of Phosphatidylinositol 3-kinase
Tang J., Wen Q., Sun J., Zhang W., Zhu H.
Type II Kinase Inhibitors: An Opportunity in Cancer for Rational Design
Blanc J., Geney R., Menet C.
Targeting Sphingosine-1-Phosphate in Hematologic Malignancies
E. Stevenson C., Takabe K., Nagahashi M., Milstien S., Spiegel S.
FAK and WNT Signaling: The Meeting of Two Pathways in Cancer and Development
Fonar Y., Frank D.
Focal Adhesion Kinase as a Therapeutic Target of Bortezomib
Ko B., Chang T., Liou J.
Novel Arcyriaflavin-A Derivatives as PIM Kinase Inhibitors for Treating Cancer
De S.
Therapeutic Potential of Targeting PAK Signaling
Senapedis W., Crochiere M., Baloglu E., Landesman Y.
Erlotinib and Gefitinib for Elderly Patients with Advanced Non-small-cell Lung Cancer
Passaro A., Alesini D., Pochesci A., Cortesi E.
Recombinant Snake Venom Cystatin Inhibits Tumor Angiogenesis in vitro and in vivo Associated with Downregulation of VEGF-A165, Flt-1 and bFGF
Xie Q., Tang N., Wan R., Qi Y., Lin X., Lin J.
Current and Emerging Strategies in Bladder Cancer
Carradori S., Cristini C., Secci D., Gulia C., Gentile V., Battista Di Pierro G.
Sphingolipid Signaling and Hematopoietic Malignancies: To the Rheostat and Beyond
C. Loh K., Baldwin D., D. Saba J.
Clinical Importance and Potential Use of Small Molecule Inhibitors of Focal Adhesion Kinase
Schultze A., Fiedler W.
Protein Phosphatase 2A as a Potential Target for Anticancer Therapy
Kalev P., A. Sablina A.
FAK and Interacting Proteins as Therapeutic Targets in Pancreatic Cancer
A. Ucar D., N. Hochwald S.
The Applications of Targeting Anti-Cancer Agents in Cancer Therapeutics
Sun G., Yang X., Yu Y., Zhao D.
Cordycepin Suppresses Integrin/FAK Signaling and Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma
Yao W., Ko B., Liu T., Liang S., Liu C., Lu Y., Tzean S., Shen T., Liou J.
The Role of Focal Adhesion Kinase in Lung Cancer
K. Dy G.
Synthesis of Cis-Fused Pyran Indolocarbazole Derivatives that Inhibit FLT3 Kinase and the DNA Damage Kinase, Checkpoint Kinase 1
Guyard-Daumas C., Sciberras S., Fouache C., Plantier S., Studeny A., Bossard C., J. Casara P., M. Golsteyn R., M. Perron-Sierra F., Kucharkzyk N., Boucley C.
Targeting Receptor Tyrosine Kinase Pathways in Hepatocellular Carcinoma
Wen Chong L., Anh Tuan Luu D., Tzen Jong C., Wei Ling Lam I., Huynh H., Wei Jie Ong R., Yi Qing Li P., Shean Lee S., Yang S.
Focal Adhesion Kinase as a Cancer Therapy Target
M. Golubovskaya V.
Novel 5-bromoindole-2-carboxylic Acid Derivatives as EGFR Inhibitors: Synthesis, Docking Study, and Structure Activity Relationship
Hassan O., Kubba A., Tahtamouni L.
Current Molecularly Targeting Therapies in NSCLC and Melanoma
Rajanna S., Rastogi I., Wojdyla L., Furo H., Kulesza A., Lin L., Sheu B., rakes M., Ivanovich M., Puri N.
MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells
Golubovskaya V., Sumbler B., Ho B., Yemma M., Cance W.
FAK and Nanog Cross Talk with p53 in Cancer Stem Cells
M. Golubovskaya V.
Cordycepin Suppresses Integrin/FAK Signaling and Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma
Yao W., Ko B., Liu T., Liang S., Liu C., Lu Y., Tzean S., Shen T., Liou J.
1 - 71 of 71 Items

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