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Advances in the Researches on the Biological Activities and Inhibitors of Phosphatidylinositol 3-kinase
Tang J., Wen Q., Sun J., Zhang W., Zhu H.
Potential Molecular Targeted Therapeutics: Role of PI3-K/Akt/mTOR Inhibition in Cancer
Sokolowski K., Koprowski S., Kunnimalaiyaan S., Balamurugan M., Gamblin T., Kunnimalaiyaan M.
Hitting the Golden TORget: Curcumin's Effects on mTOR Signaling
Beevers C., Zhou H., Huang S.
Genistein Potentiates the Anti-cancer Effects of Gemcitabine in Human Osteosarcoma via the Downregulation of Akt and Nuclear Factor-κB Pathway
Liang C., Li H., Shen C., Lai J., Shi Z., Liu B., Tao H.
Exploiting Cyclooxygenase-(in)Dependent Properties of COX-2 Inhibitors for Malignant Glioma Therapy
H. Schonthal A.
Triptolide Induces Apoptosis and Autophagy in Cutaneous Squamous Cell Carcinoma via Akt/mTOR Pathway
Zheng Z., Yan G., Xi N., Xu X., Zeng Q., Wu Y., Zheng Y., Zhang G., Wang X.
Preparation of Lycium barbarum Active Glycopeptide and Investigation of Its Apoptotic Effects on Melanoma
Qi J., Qi X., Chen H., Rui W.
The Membrane-targeted Alkylphosphocholine Erufosine Interferes with Survival Signals from the Extracellular Matrix
Chometon G., Cappuccini F., Raducanu A., Aumailley M., Jendrossek V.
Targeting the PI3K/Akt/mTOR Axis by Apigenin for Cancer Prevention
Tong X., Pelling J.
Genistein and its Synthetic Analogs as Anticancer Agents
Li Q., Li C., Li Z., Zhu H.
Therapeutic Exploitation of Apoptosis and Autophagy for Glioblastoma
Kogel D., Fulda S., Mittelbronn M.
p-Coumaric Acid Inhibits Osteosarcoma Growth by Inhibiting PI3K/Akt Signaling Pathway
Yang B., Wang B., Wang G., Cao W., Wang Q., Pu H., An W.
The Role of Serine Protease 8 in Mediating Gefitinib Resistance in Non-small Cell Lung Cancer
Gao H., Geng X., Wang L., Zhao C., Liang Z., Xing E.
Natural Products Targeting Autophagy via the PI3K/Akt/mTOR Pathway as Anticancer Agents
Sun H., Wang Z., Yakisich J.
Synthesis, Selective Cancer Cytotoxicity and Mechanistic Studies of Novel Analogs of Lantadenes
Tailor N., Jaiswal V., Lan S., Lee H., Sharma M.
Pharmacologic Inhibition of mTOR Improves Lapatinib Sensitivity in HER2-Overexpressing Breast Cancer Cells with Primary Trastuzumab Resistance
S. Gayle S., L.M. Arnold S., M. O'Regan R., Nahta R.
Processed Products of Aconitum soongaricum Stapf. Inhibit the Growth of Ovarian Cancer Cells In vivo via Regulating the PI3K/AKT Signal Pathway
Li X., Tang X., Chen L., Cao X., Ailimujiang R., Li Q., Zhao F.
Anlotinib Inhibits Proliferation and Induces Apoptosis in B-cell Acute Lymphoblastic Leukemia by Targeting the BTK and AKT/mTOR Pathway
Shi X., Li S., Tang S., Lu Y.
Arnicolide D Inhibits Proliferation and Induces Apoptosis of Osteosarcoma Cells through PI3K/Akt/mTOR Pathway
Chen Z., Ni R., Hu Y., Yang Y., Tian Y.
Tocotrienols Target PI3K/Akt Signaling in Anti-Breast Cancer Therapy
Sylvester P., Ayoub N.
Antitumoral Activity of Indole-3-carbinol Cyclic tri- and Tetrameric Derivatives Mixture in Human Breast Cancer Cells: In Vitro and In Vivo Studies
Brandi G., Fraternale A., Lucarini S., Paiardini M., De Santi M., Cervasi B., F. Paoletti M., Galluzzi L., Duranti A., Magnani M.
Erlotinib in Glioblastoma - Lost in Translation?
Karpel-Massler G., Andrew Westhoff M., E. Kast R., Rainer Wirtz C., Halatsch M.
Capivasertib: First Approved AKT inhibitor for the Treatment of Patients with Breast Cancer
De S.
JDHY3 Inhibits Hypopharyngeal Carcinoma Cell Proliferation and Promotes Apoptosis by Inhibiting the PI3K/AKT Pathway
Dai W., Ni Z., Zhang G., Xu J., Qin X., Cao J., Liu L.
Wortmannin Inhibits Cell Growth and Induces Apoptosis in Colorectal Cancer Cells by Suppressing the PI3K/AKT Pathway
Bani N., Rahmani F., Shakour N., Amerizadeh F., Khalili-Tanha G., Khazaei M., Hassanian S.M., Kerachian M.A., Abbaszadegan M.R., Mojarad M., Hadizadeh F., Ferns G., Avan A.
Targeting mTOR: Evaluating the Therapeutic Potential of Resveratrol for Cancer Treatment
Wu Y., Liu F.
Metformin: A Rising Star to Fight the Epithelial Mesenchymal Transition in Oncology
Barriere G., Tartary M., Rigaud M.
Targeting Receptor Tyrosine Kinase Pathways in Hepatocellular Carcinoma
Wen Chong L., Anh Tuan Luu D., Tzen Jong C., Wei Ling Lam I., Huynh H., Wei Jie Ong R., Yi Qing Li P., Shean Lee S., Yang S.
Effects of Citrus-derived Diosmetin on Melanoma: Induction of Apoptosis and Autophagy Mediated by PI3K/Akt/mTOR Pathway Inhibition
Li j., Xu M., Wu N., Wu F., Chen J., Xu X., Tan F., Liu Y.
Propofol and Sevoflurane Alleviate Malignant Biological Behavior and Cisplatin Resistance of Xuanwei Lung Adenocarcinoma by Modulating the Wnt/β-catenin Pathway and PI3K/AKT Pathway
Quan Y., Li S., Wang Y., Liu G., Lv Z., Wang Z.
Inhibition of mTOR Signaling by Quercetin in Cancer Treatment and Prevention
Bruning A.
The Role of Mesothelin in Tumor Progression and Targeted Therapy
Tang Z., Qian M., Ho M.
Targeting Phosphoinositide 3-Kinase Pathways in Pancreatic Cancer – from Molecular Signalling to Clinical Trials
Falasca M., Selvaggi F., Buus R., Sulpizio S., E. Edling C.
Knockdown of PROM2 Enhances Paclitaxel Sensitivity in Endometrial Cancer Cells by Regulating the AKT/FOXO1 Pathway
Jiang J., Zhang C., Wang J., Zhu Y., Wang X., Mao P.
Indirubin, an Active Component of Indigo Naturalis, Exhibits Inhibitory Effects on Leukemia Cells via Targeting HSP90AA1 and PI3K/Akt Pathway
Yao Y., Li X., Yang X., Mou H., Wei L.
Tumorspheres Derived from HCC Cells are Enriched with Cancer Stem Cell-like Cells and Present High Chemoresistance Dependent on the Akt Pathway
Zhang X., Jia Q., Lv L., Deng T., Gao J.
Deregulation of PI3K/Akt/mTOR Signaling Pathways by Isoflavones and its Implication in Cancer Treatment
Ahmad A., Biersack B., Li Y., Kong D., Bao B., Schobert R., Padhye S., Sarkar F.
Myricetin Induces Apoptosis in HepG2 Cells Through Akt/p70S6K/Bad Signaling and Mitochondrial Apoptotic Pathway
Zhang X., Chen S., Tang L., Shen Y., Luo L., Xu C., Liu Q., Li D.
Protein Kinase B/AKT and Focal Adhesion Kinase: Two Close Signaling Partners in Cancer
Wang S., D. Basson M.
Targeting Glutamine Metabolism through Glutaminase Inhibition Suppresses Cell Proliferation and Progression in Nasopharyngeal Carcinoma
Su C., Li M., Yang Y., Wang Z., Wang Q., Wang W., Ma X., Jie R., Chen H., Li X., Lu J.
Cryptolepine Analog Exhibits Antitumor Activity against Ehrlich Ascites Carcinoma Cells in Mice via Targeting Cell Growth, Oxidative Stress, and PTEN/Akt/mTOR Signaling Pathway
El-Aarag B., Shalaan E., Ahmed A., El Sayed I., Ibrahim W.
Design and Development of Oxazol-5-Ones as Potential Partial PPAR-γ Agonist Against Cancer Cell Lines
Pal T., Joshi H., Ramaa C.
Inhibition of Akt/mTOR Signaling by the Dietary Flavonoid Fisetin
Syed D., Adhami V., Khan M., Mukhtar H.
A Novel Fusicoccin Derivative Preferentially Targets Hypoxic Tumor Cells and Inhibits Tumor Growth in Xenografts
Kawakami K., Hattori M., Inoue T., Maruyama Y., Ohkanda J., Kato N., Tongu M., Yamada T., Akimoto M., Takenaga K., Sassa T., Suzumiy J., Honma Y.
Epidermal Growth Factor Receptor as a Target for Anti-Cancer Agent Design
Cao J., Fang H., Wang B., Ma C., Xu W.
Diosgenin Glucoside Inhibits the Progression of Osteosarcoma MG-63 by Regulating the PI3K/AKT/mTOR Pathway
Ruan S., Gu L., Wang Y., Huang X., Cao H.
FN-1501 Inhibits Diffuse Large B-Cell Lymphoma Tumor Growth by Inducing Cell Cycle Arrest and Apoptosis
Feng S., Si R., Zhong B., Shen B., Du Y., Feng J., Zou D., Hu B.
1 - 47 of 47 Items

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